Bipolar Disorder Library

• DSM-5 Changes: Bipolar & Related Disorders
  The new Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) has a number of changes to bipolar disorders (also known ...
• Mood Disorders: Omega-3, SAMe, and Inositol
  The very first issue of The Carlat Report (TCR 1:1) featured an article on St. John’s Wort for the treatment of depression. ...
• Antipsychotic Updates
  Tired of industry-funded antipsychotic trials? The NIMH comes to the rescue with the "CATIE" project (Clinical Antipsychotic Trials of Intervention Effectiveness). Blissfully unindustry-funded researchers have enrolled ...
• Efficacy and Atypicals: It’s Hand-to-Hand Combat
  Things were bound to get ugly. The total market for antipsychotics is $10 billion, there are five very similar atypicals jockeying ...
• Michael D. Jibson, M.D., Ph.D. on Atypical Antipsychotics
  TCR: Dr. Jibson, how do you go about deciding which atypical antipsychotic to prescribe for a particular patient? Dr. Jibson: I ...
• Abilify: The Perfect Antipsychotic?
  Abilify (aripiprazole) is out! But you probably already know this, if your mailbox and fax machine have become as saturated with BMSfunded missives from ...
• The Trouble with Zyprexa
  Zyprexa (olanzapine) became rapidly popular after its introduction in the United States in 1996. Its structural similarity to Clozaril (clozapine) led to hopes that ...
• What to Remember About Lithium
  When it comes to Lithium, you can (thankfully) forget all about the P450 enzymes, because they don't touch this salt. Lithium enters the ...
• The Incredible, The Amazing, Lithium!
  It's an amazing metal. Not only does it treat acute mania, prevent recurrences, and treat refractory depression, but when consumed as LiCl, it ...
• This Month’s Expert: Nassir Ghaemi, M.D. On Antidepressants in Bipolar Disorder
  TCR: Dr. Ghaemi, I thought we could discuss this rather controversial issue of whether antidepressants (ADs) should ...