Modeling Schizophrenia: An In Vitro Model of a Tough Disease

In the April issue of Psychiatric Times, I discussed how adult stem cells were being used to aid in research on a neurological disorder (spinal muscular atrophy). I revisit the technology in this column, now aimed at one of molecular neuropsychiatry’s most intractable, frustrating lines of research: the molecular/cellular basis of schizophrenia.

Panic-Focused Psychodynamic Psychotherapy

Both cognitive-behavioral1-3 and pharmacological4-6 treatments for panic disorder have been found to be effective over the short term. Not all patients, however, can tolerate or fully respond to these approaches,1-3,7,8 and the...

Child & Adolescent Psychiatry

Strategies to Improve Medication Adherence in Youths

Psychopharmacology has become a cardinal feature of psychiatric treatment for adolescents in the 21st century.1,2 Successful transition of youth with psychiatric disorders from the initial treatment to long-term management is fraught with pitfalls that can sabotage success.

Novel Treatment Avenues for Bipolar Depression

Bipolar disorders are heterogeneous in phenomenology, pathoetiology, comorbidity, and treatment. These disorders are highly prevalent and often misdiagnosed and underrecognized. For bipolar patients who are correctly identified, the time from onset of...


Returning Veterans With Addictions

Members of the military returning from combat operations have high rates of substance abuse. They also often exhibit a co-occurring triad of posttraumatic stress disorder (PTSD), traumatic brain injury (TBI), and pain, which complicates the problems with substance abuse.

The Science and Politics of PTSD

The first half of the 20th century saw 2 world wars, indiscriminate aerial bombing of civilians, the dropping of the atomic bomb, and the Holocaust—all of which created intense trauma for soldiers and civilians.

Shadow: A Blow So Appalling

Here’s why it is painful to see a man cry: he's not supposed to. Emotions are arresting when society tells us they should not be expressed. In the case of a grown man crying, there are some thousands of years of cultural training laying down the prohibitive regulations.