The Genetic Footprint

Clinical practice within the profession of psychology has been in the news of late as the debate on the efficacy of drug-based treatment vs. psychotherapy becomes more heated.

Recent reports on the problems with drug research, the lack of information given to clients on drug effects and the use of medication of children have projected psychotherapy into the spotlight as a safe and effective method of helping individuals in emotional distress.

Epigenetic Research

This focus puts the spotlight on clinicians who are on the front lines in treating clients and reforming the mental health system.

The field of Epigenetic research connects genetics with environment in a molecular, lasting way and it makes what clinicians do on a daily more relevant, enduring and exciting.

Epigenetics applies to the domain of the genome as well as psychology and the practice of therapy.

The field of Epigenetic research is looking at external modifications to DNA that turn genes “on” or “off.”

These modifications do not change the DNA sequence but they alter the genetic expression.

On-going experiences can become embedded in our DNA and in our long term memory and will affect our thinking, feeling and behavior in current and future situations.

Clinicians need to be aware of the significance of these findings because what clinicians do with clients in practice may well become part of the client’s molecular genetic template. The emotional interaction with clients will have long lasting impact.

For clinicians and their clients, this news, which points to the embedding of strong negative and positive client experiences in DNA and long term memory is a call for more targeted assessments and treatment.

In addition, molecular changes in our DNA may be passed down through the years and through generations as well so that the children of clients may be influenced by the changes in the DNA imprint.

Impact of Long Term Memory

Memory is a complicated and multi-faceted concept and involves various brain systems that are engaged in working memory (known as short term memory), autobiographical memory episodic memory and long term memory.

When we speak of experiences that become part of our DNA and long term memory, we refer to strong positive and negative (traumatic) memories of abuse, of birthday parties, of divorces, births, deaths and transformative therapy interactions that have an emotional impact.

These powerful experiences are most likely to be processed into long term memory and genes and therefore have an impact upon our behavior, thinking and feeling.

What our clients have experienced in their past and present and what clinicians do during the therapeutic interaction leaves a lasting footprint.

In the case of early child abuse and other traumas, we now know why experiences and memories are never lost in memory and can be reconstructed and triggered by a variety of cues that may seem imperceptible to some.

This issue is a cautionary one because the repeated triggering reinforces the memory and becomes a disabling factor. Fear cues may appear within the therapeutic context as well and this knowledge may make the clinician more observant and a better listener.

PTSD and Threatening Cues

The cycle of repeated fear arousal is PTSD and many clinicians are learning and practicing methods of treating this painful disorder.

Traumatic memories can be brought up and reconsolidated in therapy, over-written with positive or neutral information but they are never completely lost.

Research shows that certain chemicals such as valprolic acid can strengthen reconsolidation of the original fear memory or enhance long-term memory for extinction such that it becomes independent of context.

These findings have important implications for the use of medications as adjuncts to behavior therapy in the treatment of phobia and related anxiety disorders.

Some individuals are more vulnerable to PTSD because of early abuse followed by what they perceive as threatening cues during their lifetimes.

Others, who have not been sensitized, are less vulnerable but with this information clinicians need to take certain steps in treatment with sensitized clients that will be noted below.

Beyond becoming a better listener and observer, there needs to be carefully targeted evaluation of the client’s early history. Their “lived experiences” need to be done as early as possible so that sensitive clients can be identified.

Within the therapeutic relationship and within the environment that the therapy takes place, there may be fear cues that are not readily apparent. These cues may involve the receptionist’s attitude towards the client, the number of people in the waiting room, the physical dimensions of the office and of the therapist themselves.

The Genetic Footprint

Margaret Altman, LCSW, MSW

Margaret Altman is a crisis intervention specialist and has intervened in many explosive situations within jails, emergency rooms, suicide prevention centers and psychiatric units. She is a featured writer on the Mad in America website and has more more than 35 years of experience as an LCSW in psychiatry, corrections and private practice. Her book, "Developing Your Child’s Emotional Intelligence" is on Amazon. Margaret currently focuses on issues of minority and marginalized populations in order to give them a voice in the mental health domain.


APA Reference
Altman, M. (2015). The Genetic Footprint. Psych Central. Retrieved on August 9, 2020, from


Scientifically Reviewed
Last updated: 5 Oct 2015
Last reviewed: By John M. Grohol, Psy.D. on 5 Oct 2015
Published on All rights reserved.